Uhura
From TV to film, Nichelle Nichols and Zoe Saldana have portrayed the Star Trek character. However, Saldana turned the character into a main player in the new generation of films.
Static Shock
The character, created by Dwayne McDuffie for Milestone comics, went on to have an animated show and multiple solo comics.
Miles Morales
He is the first Black Spider-Man. He was created in 2011 and is voiced by Donald Glover. Now the character is a major part of the Marvel universe.